UCSD Health Sciences is a $1 billion dollar plus organization encompassing 16 academic departments (14 clinical, 2 basic sciences), 2 pre academic/hospital departments, 2 professional schools (School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences), 2 hospitals, and various other programs and units all dedicated towards fulfilling the Health Sciences missions.

The Department of Pathology plays a key role in the University's three missions. It aims to achieve the highest standards in patient care, research and education. The Department provides diagnostic pathology services in a wide variety of subspecialties with highly trained subspecialists who are recognized for their expertise. The Department's research programs are diverse and interface with a wealth of basic and translational research programs that are a hallmark of UC San Diego.

Under supervision of a physician-scientist Principal investigator (PI), lead a highly complex research project examining chromatin and epigenetics dysregulation in mouse models of neurodevelopmental disorders. Design, execute and analyze a variety of next generation sequencing methods aimed to understand epigenetic dysregulation in the developing mammalian brain. Perform behavioral analysis of mouse mutants to assess learning and memory. Examine cell-intrinsic neurodevelopment using mainly imaging approaches in vivo and in primary neuronal culture. Perform an array of standard methods in molecular biology and biochemistry.

• Strong theoretical and practical knowledge in molecular biology techniques and genetics.

• Demonstrated experience making decisions, analyzing situations, problem solving, and initiating action necessary to lead a project.

• Willingness to learn new theory, techniques, and tasks and share knowledge.

• Experience in computational analysis of next-generation sequencing data, including the use of scripts, the Python and R programming languages.

• Demonstrated experience with software applications, such as Microsoft Office, Photoshop, Acrobat and Graphpad.

• Demonstrated organizational skills to order and maintain lab reagents and supplies and keep accurate lab records and computer files. Experience in ordering, maintaining, troubleshooting, and calibrating general laboratory equipment (e.g. centrifuges, incubators, microscopes, water baths, etc).

• Knowledge of proper formats, grammar, and spelling in English and proofreading ability sufficient to compose, edit, and publish professional correspondence as well as effectively and accurately document research procedures. Ability to read, comprehend, discuss, and present research materials.

• Demonstrated experience making independent decisions, analyzing situations, problem solving, and initiating action for laboratory maintenance. Proven ability to work independently.

• Theoretical and practical knowledge of safety techniques and practices. Demonstrated ability to follow established Safety and Biohazardous Material Guidelines and implement measures to ensure compliance and maintain associated records.

• Must be able to work nights and weekends, with biological and chemical hazards, and with mice and mouse tissue.

• Employment is subject to a criminal background check.